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Further prospective studies addressing these issues will be needed.
However, the prospective data addressing these issues in eastern populations remain quite limited.
Nevertheless, prospective studies addressing this issue should be conducted in the future assessing the impact of the time of the fracture and the site.
However, so far there are no prospective studies addressing this issue, and BiDirect will be in the first line to closing this gap.
This prospective study addressed two issues relevant to the management of DLBCL in the elderly.
However, to address these issues, future prospective studies with large sample size and even randomized clinical trials may be necessary.
The clinical benefit of functional/molecular image guidance in the form of improved local control or decreased normal organ toxicity has yet to be shown and awaits prospective clinical trials addressing this issue.
However, a prospective study specifically addressing this issue did not show any effect of within-day glucose fluctuations on cardiovascular events (8).
Prospective, multicenter cohort studies addressing these important issues are urgently needed.
Between July 1997 and December 1999, we performed the first prospective randomized clinical trial addressing this issue in 159 HSCT recipients who received a prophylactic platelet transfusion when the morning platelet count fell below a 10,000/microL (10K) or 20,000/microL (20K) threshold.
The first prospective collection of data addressing the issue of antracyclines safety profile in pregnancy was first reported by the Texas MD Anderson Cancer Center back in 1999.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com