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Instituting methods of quality assurance, such as verification of registered e-mail addresses using a unique registration number would be a valuable means of ensuring information initially entered into the trial's registration profile is valid.
Residential proximity to major roads was estimated based on participants' geocoded baseline residential addresses using a geographic information system (GIS).
We geocoded participant addresses using a commercial service (Mapping Analytics LLC, Rochester, NY), which assigned a latitude and longitude coordinate to each address.
6 7 Long-term exposure to source-specific air pollution was estimated at each participant's historical home addresses using a geographical information system as described previously.
Individual-level data on numerous self-reported medical conditions and confounding variables were linked to exposure estimates at residential addresses using a validated national land-use regression model.
The daily surface concentrations of PM and ozone (O3) for the period from November 2000 through July 2003 were assigned to the participants' addresses using a geographic information system (ArcView, version 9.2; ESRI, Redlands, CA, USA).
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