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– Pain points: The major pain points that need to be addressed: complexity is one.
This model speaks to the previously addressed complexity associated with post-translational modifications of tau, and underscores that we are still at the beginning of understanding which enzymes regulate tau acetylation and deacetylation events, and more specifically how tau modifications associated with acetylation govern tau biology.
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The two obvious pitfalls are a failure to address complexity and failure to apply effective financial discipline to IT ownership.
The first place to address complexity is to try to get the tax system out of the business of deciding who is a family, said William A. Niskanen, chairman of the Cato Institute, a libertarian research group in Washington.
Special accent is given to X-ray diffraction data addressing complexity and limitations on data analysis and interpretation for low atomic number, multiphase, textured and disordered samples.
To effectively address complexity requires a planning process that embraces complexity, rather than a pre-determined management system designed for simplicity (Savory 1999).
It describes the motivation for systems engineering, introduces the systems engineering process, and then describes a simplified automobile design example to highlight how the process addresses complexity.
Our work makes a methodological contribution by adopting and validating a combination of techniques that is able to address complexity and emergence in value co-creation systems.
Using multiple methods to address complexity demands triangulation.
Existing frameworks for ATM do not address complexity of barriers and their interconnectedness.
and collaboration between various sectors to address complexity of SDH in Indigenous populations are suggested.
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