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This would suggest that the modifications remaining in H. volcanii tRNA are also critical for functions that cannot be replaced by salt and we are currently mutating all the corresponding genes to address the functional of these modifications in vivo.
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To address the functional significance of tyrosine phosphorylation of PKCδ in platelets, we used the Src family kinase inhibitor PP2 to inhibit tyrosine phosphorylation of PKCδ (Fig 3A) [13], [13].
To address the functional consequence of the G1485A mutation of Sl-eIF4E1 for cap-binding activity, soluble protein extracts of the Hm-WT and the G1485A mutant line were purified by affinity chromatography on m7G-sepharose column.
Current treatments of VML are not able to address the functional deficiency of the damaged muscles due to a lack of effective regeneration.
Here, we address the functional role of this membrane condensation in the activation of T lymphocytes.
We seek to experimentally identify the mechanism and rule of this plasticity and numerically address the functional significance of this plasticity.
Results Here, the authors test the applicability of EphA3-null mice to address the functional importance of EPHA3 in mutant Kras- or p53-loss-driven mouse lung adenocarcinomas.
To address the functional significance of TLR2 and TLR4 in the pathogenesis of DN directly, Tlr2 −/− and Tlr4 −/− mice were used.
To address the functional consequence of this loss, we examined the reciprocal effect of overexpression in cell lines that had little or no endogenous expression.
To address the functional deficit of RGCs after crush, we analyzed the effects of hNRN1 on preserving RGC function following ON injury.
To address the functional role of the UIM-containing proteins in controlling the endocytosis of ubiquitinated FcεRI complexes and their sorting along the endocytic machinery, we used small interfering RNA (siRNA -based approachesiRNA -basedith fluorescence microscopy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com