Sentence examples for address the functional impact from inspiring English sources

As there may be multiple mutations for one particular patient, it is essential to address the functional impact of a missense mutation in a model system.

Only one previous study has attempted to address the functional impact of chronic harvest site pain.

To address the functional impact of TGF- β1-induced uPA production on the progression of prostate cancer in the microenvironment of SV, it would be absolutely necessary to perform further experiments characterising changes in malignant phenotype of PC3 cells both in vitro and in vivo before and after the inactivation of TGF- β1 and/or uPA.

In this study we addressed the functional impact of alternative splicing in plants using a comparative analysis approach.

Still, these studies suffer of some limitations: more data are available on the male than on the female germline, and only few of them carried out the analyses at the most informative genome scale, addressed the functional impact of epigenetic changes on the gene expression level and related cell pathways, and took into consideration dose-effect relationships.

As most wild boars are seropositive to the RTX toxin-producing bacterium Actinobacillus pleuropneumoniae and because they have sustained continuous natural selection, future studies addressing the functional impact of these polymorphisms could bring interesting new information on the physiopathology of Actinobacillus pleuropneumoniae-associated pneumonia in domestic pigs.

Despite important progress made in the field, several important questions remain to be addressed before we fully understand the functional impact of the interaction between inflammation and epigenome deregulation in liver tissue and define the precise underlying mechanisms.

This is the first report which demonstrates the functional impact of disrupting cleavage at position 667, which had not been addressed before.

Furthermore, while we did assess depression and insomnia, which accounted for some of the functional impact of DSPS in the present study, there may be other covariates not addressed in the current study that may explain parts of this association.

This situation needs to be addressed urgently, especially in light of the rapid development of interventions to both reduce the stroke risk and the functional impact following stroke in the general population.

The functional impact of the mutation is not well documented.