Sentence examples similar to address substantial difficulties from inspiring English sources

Adding accurate laboratory testing data to ILI addresses the otherwise substantial difficulty in estimating ILI consultations due to influenza, and results in estimates that are less sensitive to parameter misspecification.

While the problem of added predictive value has long been addressed in the literature for low-dimensional models, literature on added predictive value of signatures derived from high-dimensional data is scarce [ 11], although the high dimension of the predictor space adds substantial difficulties that have to be addressed by adapting classical methods.

Participants encountered substantial difficulties with the inflexibility of the diagnostic equipment.

Substantial difficulties due to nonidentical relative degrees and directed interaction graphs are surmounted in this result.

The membrane itself may play a role but creates substantial difficulties for structural studies.

"There are substantial difficulties in prosecuting cases committed in war zones," the official said.

Their preparation can be achieved without substantial difficulties.

This can cause substantial difficulties in obtaining results which are easily presentable.

Much of the problem arises from the substantial difficulties that media faces in China.

This estimation did not pose substantial difficulties.

When a given causal variant is ultra-rare, however, this presents substantial difficulties.