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The phrase "address a large proportion" is correct and usable in written English.
It can be used when discussing the need to deal with or respond to a significant part of a group or issue.
Example: "The new policy aims to address a large proportion of the community's concerns regarding public safety."
Alternatives: "tackle a significant portion" or "respond to a major segment".
Exact(3)
Our findings suggested that investment in primary and secondary prevention could address a large proportion of avoidable RTI deaths.
7 However, this strategy does not address a large proportion of deaths that occur on the first day, such as those due to birth asphyxia and those that happen before the CBA has had a chance to visit.
Acute medicine is the fastest growing medical specialty in the UK, and with the majority of all acute admissions now presenting through MAUs, tackling AKI in this clinical setting provides a unique opportunity to address a large proportion of the well-reported deficiencies in clinical care.
Similar(57)
Of the different search techniques used to address software maintenance, a large proportion of the analyzed literature used EAs.
Traffic is a major source of local air pollution, and although the exposure assessment methods have become better in recent years, most studies still estimate exposure only at the home address, even if a large proportion of traffic exposure, especially for adults, occurs during commuting time and at the workplace.
The frenzy for acquiring Internet addresses has generally died down, but anecdotal evidence suggests that a large proportion of Internet addresses are still bought by speculators who hope to resell these names at a profit, or by individuals and companies that have registered names solely to prevent others from using them.
Because study participants were recruited from all registered births based on birth certificate addresses, we were unable to contact a large proportion of the mothers, allowing for potential response bias in our study.
Therefore, there is a need to prioritise public health expenditure to address the exceedingly high OOPE incurred by a large proportion of women for maternity care.
This illustrates that abnormalities were not only noted and documented at the checks, but that action was taken in a large proportion of children to address these issues appropriately.
The Houston Teachers Institute works with 20 self-selected middle and high schools enrolling 31,300 students to establish a program that will address the needs of an ethnically mixed student-body, a large proportion of whom are non-English speaking.
Sacramento was chosen because of its great racial and ethnic diversity, and the South Carolina counties because of a large proportion of rural route and box number addresses.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com