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Authors of some papers about cancer risks near nuclear facilities have labeled their studies descriptive, implying that they do not address a hypothesis (Laurier and Bard 1999; Laurier et al. 2008).
We address a hypothesis that there is significant genetic diversity in Cx. annulirostris and that the identification of this diversity will shed light on the paradox that JEV can cycle on an island 70 km from mainland Australia while not establishing in Australia itself.
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This work addressed a hypothesis that interaction of lipids with the PKNs may free the protein from a compact, inhibited state, leading to enzymatic activation and downstream signalling, similar to the PKC family of kinases.
In doing so we address a standing hypothesis that scaffold anisotropy and strut flexural rigidity (stiffness) co-regulate long-term maintenance of a tenocyte phenotype.
Hydrogels have been commonly used as model systems for 3-dimensional (3-D) cell biology, as they have material properties that resemble natural extracellular matrices (ECMs), and their cell-interactive properties can be readily adapted in order to address a particular hypothesis.
It would seem that to justify such an exercise, the work must provide some fundamental new insight or at the very least clearly address a specific hypothesis.
As a core infrastructure resource, the B2B Cohort sample size was not explicitly based on the power to address a single hypothesis.
Perhaps this communication could be tested in a well-designed study to address a new hypothesis for new applications of activated protein C outside the setting of severe sepsis.
For an integrated type assay, the result addresses a study hypothesis or is measured to support an objective.
Since each single test addresses a single hypothesis, the comparison of several complementary tests allows acquiring a more complete picture.
However, a publishable study should not be merely a compilation of available sequences for a protein family of interest followed by some standard analyses, unless it specifically addresses a scientific hypothesis or question.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com