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Predictions by the MLR are simply based on linear and additive associations of the explanatory variables, and these models are not able to incorporate the nonlinearities of the parameters.
A second advantage of a Bayesian approach is that it has allowed us to give some weight to non-additive genetic associations, while still giving an appropriate weight to the more prevalent additive associations.
56 More interestingly, they found additive associations among components.
We have also shown independent but additive associations between current maternal or paternal smoking and children's BMI at age 6 7.
Assuming additive associations, the estimated HR for nonaccidental mortality corresponding to a change in exposure from the mean to the 5th percentile for all three pollutants together was 1.075 955% CI: 1.067, 1.084).
However, the magnitudes of effect for these additive associations were modest and were not reflected as statistical differences in perceived effort or reward (including self-esteem) at a working-population level over time.
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When all subjects were included in a flexible ordinal regression model that allowed for non-linear effects and interactions, we found that the American National Adult Reading Test had an independent additive association such that better performance was associated with better cognitive performance across the biomarker distribution.
And then each SNP was tested for additive association with each trait by modeling the effects of genotypes and the additional covariates including top five PCs as fixed effects, and random polygenic effects as random effects, mainly considering that our samples were from highly structured populations with strong family relatedness.
Therefore, we hypothesized that nuclear FABP7 and EGFR expression might have additive association with poor prognosis.
Severe impulsive cluster B personality disorders and alcoholism may have an additive association to deviation in trait HA.
In Equation 3, each SNP was tested in turn using a t-test (H0: No additive association between the SNP and trait), and p-values were obtained.
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