The phrase "additionally there is substantial" is correct and usable in written English.
It can be used to introduce extra information or to emphasize the importance of a point being made.
Example: "Additionally, there is substantial evidence to support the theory proposed by the researchers."
Alternatives: "Furthermore, there is considerable" or "Moreover, there is significant".
Additionally, there is substantial evidence implicating a role of IL-6 in the pathogenesis of cancer cachexia [ 5].
Additionally, there is substantial expenditure for vector control programs each year (e.g., > $10 million in Queensland in 2004 alone) (Tomerini 2007).
Additionally, there is substantial evidence that RNAi is employed by cells as a mean to keep mammalian endogenous retroviruses (i.e. retrotransposons) under check [ 41- 46].
Additionally, there was substantial variability in the big home profile with a high number of contacts at home: it was found rarely in Germany, Netherlands and Poland.
Futhermore, fewer than 7% of children treated with an antimalarial for fever were administered therapy containing artemisinin, despite the adoption in 2005 of artesunate-amodiaquine as first-line recommended therapy [6]; additionally, there was substantial use of poorly-tolerated (quinine) [19] and ineffective (sulfadoxine-pyrimethamine) antimalarials [20].
Additionally, there are substantial barriers to pregnant women engaging in intensive lifestyle intervention programs [ 13, 14].
Additionally, there was substantial variation in duration of treatment owing to the individual patient variations in timing of study entry and the timing of availability and transition to commercial therapy.
Additionally, there is a substantial amount of literature stating the direct correlation between historic preservation and the overall economic growth of neighborhoods.
Additionally, there is no substantial difference in antifungal susceptibilities between the P. capsulatum strains isolated from environmental sources and the CBS 134186 isolate (Additional file 1: Table S1).
There is substantial variation across countries.
There is substantial variation by site.
