Additionally, nucleosomal occupancy may differ at other points of the life cycle not represented in our dataset, during which some genes are most highly expressed.
Additionally, H3K27ac occupancy also correlates well with gene expression in general apart from at p63 binding sites (median Pearson's R = 0.72) (Fig 2B), which is consistent with previous reports of the correlation of H3K27ac with gene transcription [ 34].
100 To characterize the molecular crosstalk between ERG and AR, studies showed that ERG can effectively attenuate AR signaling by the direct transcriptional repression of AR, and additionally ERG occupancy at AR target genes correlates with negative regulation, which is potentiated by ERG-induced EZH2 activity.
Additionally, increased nucleosome occupancy was observed at numerous promoter sites throughout the yeast genome upon Abf1 depletion, indicating that Abf1 maintains an open chromatin conformation at its binding sites (Badis et al. 2008; Ganapathi et al. 2011; Hartley and Madhani 2009).
Additionally, 5-HT1A and 5-HT7 occupancies were determined as described below.
Additionally Pol2 ChIP-Seq binding occupancy signal was observed mainly within a 500 bp window around the main TSS of all CAGE-derived human promoters [ 9].
Additionally, in the absence of Cyc8 Tup1, the occupancy of the HDACs, Rpd3p and Hda1p decreases in parallel with an increase in the occupancy of Swi Snf at the site formerly occupied by Cyc8 Tup1.
Additionally, the consomic strains showed differential genomic occupancy of androgen receptors in cardiac chromatin from intact adult mice and in neonatal hearts.
Additionally, one Br− site (site Br1) at 44% occupancy is observed in the distal-heme cavity at 5 Å from the heme iron.
Additionally, symmetrical analysis (SA) of the possible hydrogen occupancies and related distortions of the coordination polyhedra are discussed and placed in the context of the experimental data.
