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Additional subjects are needed for future studies.
If dose limiting toxicity (DLT) is not observed in any of the subjects, three additional subjects are registered and given a higher dose and the test continues.
Subjects are told that they may have to wait a short time for classes to begin while additional subjects are being recruited.
In view of our data, we conclude that both WHO and IDF definitions identify patients with insulin resistance and increased cardiovascular risks factors, but IDF definition identifies additional subjects, not identified by WHO definition and these additional subjects are at increased cardiovascular disease risk with lesser degree of insulin resistance.
Similar(56)
Ten additional subjects were asked to indicate their BPD on a body chart after performing a similar experiment.
Six additional subjects were treated using the same gene transfer protocol, but after withdrawal of ERT and administration of low-dose busulfan 65-900 mg/m(2)).
Data from 11 additional subjects were excluded due to: napping for less than 20 min (3 subjects), falling asleep during the quiet wake period (7 subjects), and performing lower than 2 SD below average on the first session test (1 subject).
Because of inadequate subject recruitment, additional subjects were recruited during race registration held the day before the race start.
The PK population consisted of 12 subjects after two additional subjects were excluded: one due to pre-dose concentrations greater than 5% of Cmax in both treatment periods, and one due to a pre-dose concentration greater than 5% of Cmax during the first treatment period (both subjects had participated in an earlier fingolimod study which caused pre-dose values in period 1).
Ten additional subjects were initially tested.
Four additional subjects were removed from the analysis due to movement artifacts.
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CEO of Professional Science Editing for Scientists @ prosciediting.com