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Additional studies utilizing air toxics in addition to criteria pollutant data and source-specific information on pollutant contributions would provide further evidence on how and which air pollutants impact fetal development and may help inform regulatory policy decisions.
However, we have conducted additional studies utilizing the same Nestin-CreERT2 line to target adult-born neurons, where we see that x-irradiation prevents the electrophysiological impact of these cells on hippocampal circuits, ruling out the possibility that ectopic expression through this driver line affects hippocampal activity (unpublished results).
Resolution of the motivational vs. social origin interpretation of observed gender differences will require additional studies utilizing various types of esthetic stimuli.
Therefore, additional studies utilizing this approach will be needed to evaluate its applicability to other domains.
Additional studies utilizing fluorescent dye labeling of neurons and an in vitro migratory assay with DiI showed that these interneurons display the same migratory pattern from the ganglionic eminence to the mature cerebral cortex [ 74, 75].
Given the limited information on BPA exposure and ovarian steroidogenesis in women and the discrepant study results, additional studies utilizing sensitive and reliable steroid hormone and BPA assays are required to delineate whether BPA levels negatively impact reproductive hormonal patterns in women.
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Additional studies utilized inducible cardiac Sav1 and Lats1/2 CKO mice to test whether these Hippo pathway components could also influence the regenerative capacity of the mammalian heart [125].
For the purpose of an additional study utilizing the same data collection, the sampling procedure was not randomised but stratified.
Additional preclinical studies utilizing such tracking technologies will allow us to track transplanted cells over extended time periods to identify the limits of cell survival in vivo, and assess alternative immunosuppression paradigms if necessary.
While additional prospective studies utilizing drug PK data are urgently required, clinical trials examining the efficacy of new agents in this setting must be cognisant of these findings [ 6].
Additional in vivo studies utilizing site-specific knockin animals are needed to investigate the physiological importance of the His regulatory site, as well as its role in pain disorders, which would provide a better understanding of the function of endogenous chelators of the CaV3.2 channel in nociceptive transmission.
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