Exact(7)
This additional stringency of collecting just the top 1% of CD4+CD25high cells as Tregs ensured removal of most of the activated CD25low T-cells.
With this additional stringency for peak calling, it could be that the negative regions as defined by this meta approach harbor enriched regions that could possibly represent true binding sites of lesser affinity to the TF.
The complete set of confirmed, high confidence, and potential novel miRNA candidates, as well as the rest of the candidates out of the original list of 132 putative novel miRNAs that failed our additional stringency criteria, are provided as Supporting Data File S1.
Without an ability to understand the potential benefit (or lack thereof) of the additional stringency, an appropriate consideration of benefits and costs is not possible.
In the original UC-DAI, mucosal friability is allowed at a score of 1; however, for additional stringency, we excluded any patient with mild mucosal friability on endoscopy.
For additional stringency, genes with a deviation of less than 40 reads per million between pre- and post-inoculation levels were filtered out to create an additional gene list.
Similar(53)
While companies may not have to comply just yet to additional regulatory stringency, they must begin to weigh how to protect data across their corporate infrastructures.
For these introns only, an additional lower stringency screen (P ≤ 0.001) was used to recover repetitive elements of potential importance.
Elution using a salt gradient provides additional wash stringency prior to peak elution and results in improved purity.
5T4 is up-regulated at an earlier stage of ES differentiation than the widely used down-regulation of the SSEA-1 marker [13] while cell sorting for surface 5T4 expression provided an additional level of stringency in the definition of ES cell populations compared to stratifications used in some other microarray studies [19], [20].
Finally, we introduce an additional level of stringency by requiring a minimum frequency of MCD in the given cohort.
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