The phrase "additional sites of action" is correct and usable in written English.
It can be used in contexts discussing pharmacology, biology, or any field where multiple locations or mechanisms of effect are relevant.
Example: "The new drug has been shown to have additional sites of action beyond its primary target, enhancing its therapeutic effects."
Alternatives: "extra points of action" or "further sites of effect".
However, the discovery of additional sites of action for endocannabinoids as well as synthetic cannabinoid compounds suggests the existence of additional cannabinoid receptors.
It might also suggest additional sites of action for systemic agents, such as glucocorticoids, that control neurogenesis [8].
For this reason, the fact that BTS-2 acts in the same order of magnitude as doxorubicin against K-562 tumour cells and also against normal HLFs that should have a low or even absent tNOX activity rises the possibility of additional sites of action for this drug.
Because of this, it can be speculated an additional site of action of PHMB which impairs the HSPG-HPV binding in the BM counteracting the viral infection process.
Although the cannulae were positioned in the VPL, further objective measurements of the spread of the JWH-133 into adjacent brain areas would be required to discount additional local sites of action.
Furthermore MR-angiography is useful in determining the vascular site-of-action of vasoactive substances.
TRPV1 expression has also been reported in human dendritic cells (DCs), where its activation suppresses differentiation, providing an additional potential site of action during allergic contact dermatitis.
Because of the widespread expression of HSPGs, sites of action for antithrombin may not be restricted to endothelium and leucocytes but may well include additional targets.
Drug interactions may reveal mechanisms of drug action: additive interactions suggest a common site of action, and synergistic interactions suggest different sites of action.
However, several modes of action as well as multiple sites of action have been proposed.[3].
Analysis of the physicochemical properties of antibacterials is further complicated by their varying sites of action.
