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Interestingly, both rATG and alemtuzumab induced degranulation of NK cells without additional sensitization by adding K562 cells.
However, the role of IFN-γ in TSS without any additional sensitization protocols has not been thoroughly investigated using animal models that recapitulate human TSS.
Notably, the concentration of egg white-specific IgE was significantly increased (P = 0.015) in the group of patients displaying additional sensitization to yolk (median 3.56 µg/ml versus 1.02 µg/ml).
These case reports reveal that recombinant forms of TRAIL, and possibly other TRAs, can be beneficial for individual patients even without additional sensitization strategies.
This cellular infiltration of the bladder with granulocytes and macrophages was not substantially altered by additional sensitization of the mice with PstS1-loaded particles (group 6, table 2).
Additional sensitization by either blocking protein biosynthesis with cycloheximide or incubation with the phytochemical resveratrol is needed to finally execute the apoptotic program.
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Although additional yolk sensitization does not seem to cause more severe symptoms, it may worsen life quality because it enlarges dietary restrictions.
Additional community sensitization activities targeting women and their families may also be helpful to emphasize key instructions about when to take the medicine.
Importantly, the three additional bouts of sensitization training did not induce LTM in naïve animals (Control-Veh-3XTrained; Figure 7B).
Comparison of the GO biological processes among allergen sensitized groups revealed a total of 46 overlapping biological processes commonly enriched (p < 0.05) in response to BLG, OVA and PNA sensitizations (Additional file 6).
As ViL alone shows only slight insulin sensitization, the additional effect of VaL in ameliorating stress signals in liver could explain this additional benefit.
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