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Several other differentially expressed genes identified in the ENCODE tiling array analysis were selected for qPCR analysis using additional patient samples.
49 additional patient samples were selected but not used for analysis.
Additional patient samples will be needed to confirm this finding in a replication study.
Additional patient samples for which outcomes were known, were obtained from a sample bank to ensure sufficient statistical power.
Additional patient samples would also help determine if it is possible to accurately measure exon 1A3 transcripts with the bDNA assay.
Analysis of additional patient samples, which are rare, will be of value in determining the degree to which this occurs in the general population of type I diabetics.
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A non-conserved STAG2 mutation, E20Q, was found in one additional patient sample.
Three additional premalignant patient samples were obtained from brushes taken at the Pathology Department in Morriston Hospital from surgical resections.
To further explore the cytotoxic properties of AKN-028, and to compare it with the specific FLT3-inhibitor AC220, 11 additional AML patient samples were analyzed by the FMCA (Table 1, Figures 4a f).
Specifically, the analysis results of TCGA GBM data in this study are being considered to subtype additional GBM patient samples from TCGA as well as GBM xenograft models with drug response information.
That's where additional measurements on patient samples, big data analytics, and machine learning come in.
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