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Moreover, some Chinese waxy accessions without the two wx deletions were also identified (data not shown), which suggests that there may be additional origins of Chinese waxy maize.
In our study, we did not see this cell migration, so additional origins of the amoebocytes should be considered; amoebocytes may be proliferating at the site of infection or differentiating from a naive stem cell population often referred to as undifferentiated amoebocytes [16], [34].
More specifically, in cells irradiated in early S phase, Rb was found associated with an early firing origin of DNA replication (the Lamin B2 origin) during the S-phase block, and then with additional origins in the order in which they fired [9].
However, CFS are unable to compensate for replication stress, and the inability to activate additional origins may impede the completion of replication leading to CFS destabilization.
These apparently less constrained features of the Sulfolobus genome structure may have imparted greater plasticity to replicon evolution in Sulfolobus, thus making ancestral Sulfolobus chromosomes receptive to additional origins of replication.
The exact localization of origins on the sequences of EtoL domains could clarify whether the additional origins accuired upon the EtoL transition during differentiation of pluripotent hESCs are L1-associated.
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In rat cerebral cortex, CART-positive/MCH-negative axons were very rare [see 10], suggesting an additional origin for the innervations by CART axons in mouse cerebral cortex.
Because SAC3 deletion restores replicon progression at early origins without exhibiting additional origin-unrelated BrdU peaks, we conclude that Sac3 ablation somewhat stabilizes genome-wide rad53 forks.
An additional origin of high background signals in microarray analysis is caused by the occurrence of non-unique sequences on the chromosomes.
Some authors assume that lymphatic vessels are exclusively derived by sprouting from the venous system, whereas others suggest that there is an additional origin from mesenchymal lymphangioblasts [ 25].
We present a Bayesian genetic approach that suggests that the duplicated control region can function as an additional origin of heavy strand replication.
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