The phrase "additional level of regulation" is correct and usable in written English.
It can be used when discussing the need for more oversight or control in a particular context, such as legal, financial, or organizational matters.
Example: "The new policy introduces an additional level of regulation to ensure compliance with safety standards."
Alternatives: "extra layer of regulation" or "further degree of regulation".
Furthermore, Fmrp has been shown to directly bind the Cbl mRNA, possibly regulating its stability and translation, thus adding an additional level of regulation to Cbl gene expression [ 33].
However, an additional level of regulation is provided by epigenetic controls.
The 3D organization of the genome might, thus, provide an additional level of regulation necessary for fine-tuning gene expression.
Even though we are only beginning to understand the contribution of distinct NF-κB family members to the regulation of gene transcription in the brain, an additional level of regulation of NF-κB activity has emerged as operated by the epigenetic mechanisms modulating histone acetylation.
An additional level of regulation is introduced by the transport rates of ATP and NADH between the mitochondrial matrix and the cytoplasm.
An additional level of regulation of hBD-2 expression is the responsiveness of cells to pro-inflammatory cytokines.
This may reflect additional levels of regulation apart from filament assembly per se (Figure 6C and Figure S2).
Furthermore, genome-wide ChIP studies indicated that there are multiple sites inside BORIS exons and introns that are occupied by CTCF [40], indicating possible additional levels of regulation.
As suggested in the selective context model, additional levels of regulation appear to be necessary to mediate target gene selection, modulated by e.g. either post-translational modifications of p53, co-factors, p53-binding factors, p53 responsive microRNAs (miRNAs), p53 family members or chromatin remodeling factors.
The spatial separation of making translatable mRNPs from the translation process in eukaryotic cells has made possible additional levels of regulation of gene expression.
Additionally, class II HDACs seem to have additional levels of regulation, which makes elucidation of the mechanism of gene transcription regulation more complicated.
