Suggestions(5)
Exact(3)
Adding more input parameters will increase the accuracy for special cases; however, without access to sufficient additional exemplars, this may reduce generalization of the method.
While the genes associated with immunity are now being characterised in other insect genomes [ 7, 8], these additional exemplars do not yet span the diversity of Arthropoda.
Comments made throughout the survey as well as in response to the question about whether panel members felt any features were missing, were thematically analysed and used to develop a list of additional exemplars and features for the second round of the survey.
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In Additional file 1, exemplar quotations are reproduced exactly as written, selected to illustrate the main issues and themes raised by respondents.
Both case studies, which can serve as exemplars for additional cases, follow a standardized format in several sections: proximate mechanisms, affected population, first detailed evolutionary history and ultimate explanations and then the pathways by which evolutionary processes can affect disease risk that this example illustrates (Box 2).
Six protein targets of relevance to small molecule therapy were selected from the sc-PDB (2013) database as exemplar queries (Additional file 1: Table S1).
The full dataset consists of 473 exemplar species (Additional file 1).
Considering the combined analysis results, ancestral reconstruction of structural motifs scored from exemplar repeats (Additional files 6 and 7) showed the unambiguous presence of An motifs at the root of the tree and its loss in three independent lineages.
Moderate exemplars required some additional context for understanding.
Badapple was chosen as the first "exemplar" BARD plugin (Additional file 1), based on the scientific value of promiscuity modeling and the direct relevance to bioassay data analysis.
Additional file 1: List of exemplar taxa in study.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com