An additional disadvantage of USPIO is that it is not universally available and using USPIO for MR lymphography is 'off-label'.
An additional disadvantage of the study is the use of heparin to avoid hypercoagulability.
Additional disadvantages of MRI may be the low availability, high costs and the need for sedation in children younger than 4 6 years.
Additional disadvantage exists for consumers with persistent LBP who reside in geographically isolated regions, where there is even less access to evidence-based pain services and community support [ 12, 20].
Fossil fuels have an additional disadvantage that they are not renewable.
For mature male parr, both decreased body and gonad growth may give an additional disadvantage through reduced fertilization rates during breeding.
The separation factor for OODD was lower than the one obtained for shark liver oil and an additional disadvantage was the need for supplementary steps of purification in order to obtain similar purity of the final product.
Weight gain associated with insulin treatment is an additional disadvantage that may affect insulin sensitivity and may be counterproductive for patient motivation toward therapeutic adherence.
As parents of bilingual children, we are at an additional disadvantage.
As an additional disadvantage, the SQUID-based systems cannot be applied directly to the patient because of the need for thermal insulation due to liquid helium respectively liquid nitrogen cooling of the SQUIDs.
Additional disadvantages with the use of transfusions relate to scarcity and cost of blood.
