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Additional data was extracted on study design, sample demographics, exercise dose, frequency and duration of follow-up, included costs, chronic multimorbidity and findings.
Additional data was extracted from the records of those subjects confirmed as having lung cancer, including the date of lung cancer diagnosis, histology of the cancer, stage at presentation, survival from the date of diagnosis, and details of medication use (type and dates).
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Based on feedback from the user community regarding failure of the initially published model results for particular classes of chemicals and endpoints of interest, additional data were extracted from the literature and added to the experimental property database.
Additional data were extracted for the DH commissioned evaluation, but are not reported in this paper.
Additional data were extracted in order to assess the methodological quality of each study.
Finally, additional data were extracted from Online Mendelian Inheritance in Man, where available (see Tables 2 and 3 for details).
Additional data were extracted from the studies, including the first author, publication year, number of patients, mean age, follow-up, cancer type (system), cancer category and stage.
Additional data were extracted from external sources on malaria seasonality and the population prevalence of malaria protective genes using the geographical coordinates of each PSU (n=2604 community waypoints).
To make enrolling a large number of patients in the DD2 fast and simple, relatively few interview and clinical data are collected, and additional data are extracted from Danish population-based databases.
Additional data were extracted for studies on post-cardiac arrest patients: average delay to return of spontaneous circulation (minutes); prevalence of initial shockable rhythm (ventricular tachycardia/fibrillation); prevalence of out-of-hospital cardiac arrest; prevalence of therapeutic hypothermia.
Data was extracted from EDHS 2011 children's data set using the prepared data extraction tool (Additional file 1).
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