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In addition, an additional cost-effectiveness study would be useful to determine whether CHW interventions are a cost-effective alternative to health interventions to promote and prevent diseases.
To persuade companies to take this approach, Plata plans to do additional cost-effectiveness studies.
The rationale for this procedure is that the QALY approach is seen critical by German authorities (especially by the IQWiG) and hence using clinical markers, to provide additional cost-effectiveness outcomes, will broaden the spectrum for argumentation.
Additional cost-effectiveness analyses, accounting for these studies, might be needed.
Additional cost-effectiveness analysis of PAD interventions is needed and should be included in all future peripheral vascular device trials.
Also the value of additional cost-effectiveness information for the model parameters is likely to be low.
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The additional cost effectiveness was mainly derived from the lower total drug acquisition costs when fulvestrant is used as third-line hormonal therapy for advanced disease.
An additional cost effectiveness analysis will use the magnitude of a mean and median change on the Oswestry Disability Questionnaire as the natural unit of outcome.
Additional cost effectiveness ratios will be calculated as the total program cost per 10% change in functional independence (at discharge), and the total program and health service cost per 10% change in functional status between the control and intervention groups over a 12 month period.
Table 5 presents the additional costs, effects and cost-effectiveness of interventions for stillbirths and maternal and newborn health with default family planning scale up.
Cost-effectiveness studies commonly relate costs to effects and calculate the addition costs per unit of additional effect (incremental cost-effectiveness ratio).
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