In addition, compartmentalization of lipid classes (neutral lipid-NL) mediated by exogenous ABA (10 μM) based on the TLC plate analysis was explored (Additional file 1: Figure S1).
In addition to compartmentalization, an additional process has likely contributed to generate the complex pattern of variation in the viral populations obtained from the PS and the infected patients.
However, additional information regarding compartmentalization, cycles and expansion of previously lumped reactions has not necessarily led to improved accuracy and better predictions.
Based on these identified Cd-responsive genes, we propose an integrated schematic diagram of the mechanisms involved in Cd tolerance and adaptation and a specific model for compartmentalization (Additional file 13: Figure S3), which may provide novel clues towards the characterisation of molecular mechanisms underlying Cd tolerance in barley.
Although these computational experiments show that the cAMP microdomain can be reproduced without diffusional barriers, the identification of the exact mechanism responsible for the compartmentalization requires additional simulations.
Furthermore, we hypothesize that the general depletion of hydroxymethylation and global hypomethylation of chromosome 8 may be unrelated to gene expression regulation, instead being associated with a general mechanism of chromatin processing and compartmentalization of additional chromosomes.
This change was so profound relative to any other treatment that we were unable to discern the subcellular compartmentalization of lysosomes (Additional file 3: Figure S3).
In contrast to similar structural features between centromeric and euchromatic TRs, these two categories show clear chromosomal compartmentalization, suggesting that additional requirements may be imposed on sequences belonging to different regions.
These data support the possibility that NAD+ is compartmentalized; however, additional studies are needed, and a key step in determining the compartmentalization of NAD+ will be to establish technologies that allow direct detection of NAD+.
We propose that alteration of nuclear compartmentalization might represent an additional common mechanism of leukemogenesis.
