Additional characteristics including items from NEO, Inventory of Depression Severity (IDS) depression, and Beck Anxiety Inventory (BAI) anxiety are included in Table S1.
Moreover, the Trials cohort was selected for additional characteristics, including metabolic impairment and IAA positivity.
Additional characteristics included age, gender, Karnofsky performance score (KPS), pre-radiotherapy hemoglobin levels, tumor site, histological grading, human papilloma virus (HPV -status, T-classification, N-classification, American Joint Committee on Cancer (AJCC)-stage, extent of resection and concurrent cHPV -status.
Additional key physical characteristics include internal and external noise [ 50, 51], temperature control, exposure to light [ 52, 53], practice of developmentally supportive care [ 54], provision and extent of family-centered care, provision and extent of breastfeeding support, potential for continuous parental involvement, as well as training and preparation for discharge home.
Additional demographic characteristics included age and education.
Inclusion of additional maternal characteristics, including immigration characteristics, did not substantially alter the observed associations.
Collection of additional study characteristics including age at enrolment, blood collection and processing, stage classification and clinical follow-up were described earlier (Gann et al, 1996).
Additional clinical characteristics including airway hyperreactivity, lung function and atopic status were determined via methacholine challenge, spirometry and allergen skin test respectively as outlined previously [ 15].
By linking the Medicare data to the 2006 American Hospital Association annual survey 26 27 we obtained additional hospital characteristics, including whether each hospital was a major teaching centre, whether each hospital was or was not owned by physicians, the total number of annual admissions, and the number of hospital beds.
