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These results confirm that additional bottlenecks must be overcome to achieve higher TAG titers.
Additional bottlenecks included lack of adequate mentorship and supervision mechanisms, and knowledge and awareness of health workers.
Under conditions of elevated heme, additional bottlenecks could be identified by making use of the autofluorescence of most intermediates in the later part of heme and siroheme biosynthesis.
Additional methods such as ribosome profiling [ 82] and metabolomics [ 83] could be used to identify additional bottlenecks in central carbon metabolism that could be addressed in the future.
Moreover, these timings make it apparent that this system can be integrated in a real time surveillance system without introducing any additional bottlenecks.
Centralized HIV care at the hospital level tends to create additional bottlenecks in treatment initiation, and creates difficulties with transport and time off work for the patients [ 29, 35, 36].
Similar(53)
Moreover, the additional bottleneck for solar energy conversion by photocatalysis is that most metal oxide-based photocatalyst materials are wide-band-gap semiconductors.
Unlike Arabidopsis, rice has experienced domestication and subsequent artificial genetic improvement and therefore has been shaped by an additional bottleneck effect.
The genetic heterogeneity observed may be significantly less than that found in the native Asian population, since the founder population in the US was likely small, representing a significant bottleneck, and an additional bottleneck occurred when founding the laboratory population.
While this interpretation is necessarily speculative (and does also not rule out additional bottleneck effects), it also corroborates the findings that we made in our companion paper on comparisons between mandible shape QTLs obtained from different experiments [ 53].
Because, in principle, antibodies to more antigens could be obtained from a single mouse, we sought to reduce the amount of hybridoma supernatant required for initial antibody screening and address an additional bottleneck in this method: the identification of functional antibody-encoding plasmids.
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