The AG group is from a small population with additional European ancestry originating from 19th century German immigrants, with about 20% European admixture[7], but otherwise similar to the AC group.
For the additional European ancestry cohorts, CNV calls were made as described in the primary publications [see Supplementary Material, Table S1 and references (5, 9, 48, 49)].
We also investigated additional European ancestry cohorts for evidence of the PAK7 duplication and details on the samples tested, case and/or control numbers and genotyping platform are provided in Supplementary Material, Table S1 (5, 9, 48, 49).
Additional file 1: Ancestry models with K = 2 to 5 assumed ancestries for the dataset reduced to a maximum of 20 individuals per breed.
The Sardinians also became isolated after the agricultural transition, but they lack the additional hunter-gatherer ancestry that characterises the Basques.
This is where the concept of diagnosis comes into play: A diagnosis is a list of characters we can see on a specimen that provide insight into the nature of its ancestry (additional information on the distinction of definition and diagnosis in the context of mammal evolution can be found in Rowe 1988; de Queiroz 1994, and Padian and Angielczyk 2007).
However, there were no statistical differences in GRSS effect sizes (p > 0.138) when comparing by ancestry (Additional file 3: Table S3b).
Our data with richer taxon sampling identified another prokaryote-type subfamily with cyanobacterial ancestry (Additional file 8), illustrating the hidden evolutionary diversity of protist and algal metabolomes.
VINOs are enriched in YRI samples, providing better discrimination and counteracting ascertainment bias toward populations of European ancestry (additional files 8, 10).
If X ij = Gj for all j, then r i = 0 and there is no additional information about local ancestry beyond information about genome-wide ancestry.
