Exact(4)
Additionally, we calculated the AUC under an ROC curve in which a model including all variants (additive) is compared with a model including a two-way interaction term in addition to the variants (interaction).
In addition to the variants validated to determine specificity, validation was also targeted to several hundred substitutions involved in regions of hypermutation and dinucleotides (Table S1 B).
In addition to the variants, their genomic locations and corresponding genetic consequences, a number of trait association data (23) are also exposed.
One could argue that in addition to the variants within Adamts16, there may be other variants within inter-genic or intra-genic regions of the critical QTL interval that contribute to the QTL effect.
Similar(4)
In addition to the variant residues, our data indicate that a (H/K/N xx(S/T)(S/N K/R KK motif located immediately prior to the dimerization region is also used by class V AtFYVE domains to recognize either headgroup (Fig. 5B).
We created a series of double and triple variants in addition to the single variants H236K, H236I and H236R (see Table 3).
Low-frequency variants in LARS2 In addition to the common variants, the DIAGRAM meta-analysis also captured fourteen low-frequency SNPs (0.01 > MAF < 0.05) within the LARS2 gene, ten of which are in high linkage disequilibrium with each other (r > 0.95 according to HapMap) (ESM Fig. 1) and showed some evidence for association with type 2 diabetes (ORs 1.17 1.21; p 0.02 0.05).
In addition to the splice variants, our GenBank search predicted two more mRNA variants: one with an Ex1 located approximately 73 kb upstream from the TSS (designated E1U) and one that lacks Ex1 (that starts from Ex2, designated as E1-).
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