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In addition, substrates can either be conjugated to GSH by special enzymes or simply co-transported with GSH (Deeley et al., 2006; Zhang et al., 2003).
For example, it has been reported that tactile sensing of substrate stiffness by cells feeds back on cell adhesion and cytoskeletal organization [33], [38], and in addition, substrates that are too elastic can cause cell apoptosis [38].
In addition, substrates with a softer and tenascin-C-coated environment increase the migration and fragmentation of the primary newt muscle cells; however, environments with a stiffer and laminin- and fibronectin-coated environment enhance cell differentiation [ 23].
In addition, substrates that would generate an annealed product that is a blunt end duplex or has a 3′-ssDNA overhang should produce more product in an annealing reaction because the product should not be unwound by the 5′-to-3′ helicase activity of Pif1.
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In addition, substrate exhaustion can also be assured in fed-batch fermentation.
In addition, substrate bacteria is also essential for larval survival and development (Zurek et al. 2000).
In addition, substrate-trapping studies revealed that IRS1 is a substrate for PTP1B in brown adipocytes.
152d In addition, substrate binding promotes dimerization.
In addition, substrate binding is reported to occur through an induced-fit mechanism.
In addition, substrate specificities for PFT and PGGT1 are shown to reflect differences in catalytic turnover rates rather than differences in substrate binding.
In addition, substrate-assisted assembly was recently reported for the Fbxl3 Skp1 Cul1 complex, which requires substrate Cry1 for the in vivo formation of CRL1Fbxl3 [ 34].
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