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The barriers to siRNA delivery are well known and can be individually overcome by addition of functional modules, such as conjugation of moieties for cell penetration or targeting.
The barriers can be individually overcome by the addition of functional modules such as conjugation of moieties for cell penetration or targeting.
The clinical success of non-viral gene delivery is hampered by transfection efficiency and tumor targeting, which can be individually overcome by addition of functional modules such as cell penetration or targeting.
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A more robust approach that allows, per the additions of functional modules, to enhance traditional computer aided diagnostic systems towards a global diagnostic engine reasoning on different sources of knowledge with their uncertainties.
A more robust approach that allows, per the additions of functional modules, to enhance traditional computer aided diagnostic systems towards knowledge based systems that emphasize the whole life cycle of the vehicle.
Every IED is an integration of functional modules and has three main parts: function module (FM), local coordination module (LCM) and remote coordination module (RCM).
In addition, it has become clear that mobile elements form by a combination of functional modules, which makes it more difficult to categorize them (Toussaint & Merlin, 2002; Frost et al., 2005; Leplae et al., 2006).
In addition, other types of data, such as synteny or evolutionary information, and protein structure and families could improve the evolutionary comparison of functional modules.
Schmid, A. B. et al. The architecture of functional modules in the Hsp90 co-chaperone Sti1/Hop.
These platforms are comprised of functional modules, which are designed to work in harmony out of the box.
Functional module-based filtration selects SNPs within the same functional module and selected SNP sets are tested to measure the effect sizes of functional modules.
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