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The combination of pioglitazone with metformin resulted in better HbA1C and lipid control without added effect on inflammation, fibrinolysis, and renal function.
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Jane Tadman, of Arthritis Research UK, said: "Our own published research and that of researchers in Japan has shown a modest but significant effect on inflammation in rheumatoid arthritis, and this latest piece of research adds further evidence of this link.
The combination of both had no additional effect on inflammation.
An effect on inflammation has also been observed [ 40].
However, its effect on inflammation still remains unknown.
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