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Model 3 (fully adjusted model) added adjustment for (time dependent) stroke to model 2 to account for stroke as a potential intermediary variable between diabetes and dementia/CIND.
The final agreement fell in between, with an added adjustment demanded by House Democrats that will allow states to use some of that money for the renovation and repair of school buildings.
Sixthly, we added adjustment for circulating infectious disease levels (influenza and respiratory syncytial virus).
In model 3, we added adjustment for maternal smoking, maternal BMI at the first antenatal visit and family situation.
Separate added adjustment for height and percent fat mass did not alter results for either diabetes outcome in either sex (data not shown).
Finally, model 4 added adjustment for metropolitan area, which may reduce bias from potential confounding but may also reduce power by controlling for between-area differences in exposure variability.
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The first model adjusts for age and race, the second model adds adjustment for four lifestyle and clinical factors, and the third model adds adjustments for two occupational factors.
We also conducted sensitivity analyses adding adjustment for whether the nurse's parents owned their own home when she was born, an additional socioeconomic status indicator that reflects status in childhood.
A sensitivity analysis was made to the un-stratified Cox analyses, by adding adjustment for one modality of adjuvant therapy at the time (planned radio-therapy yes/no, planned chemo-therapy yes/no, planned antihormonal treatment yes/no).
After adding adjustment for reperfusion therapy and evidence-based treatment at discharge, there was no longer any gender difference in long-term mortality (HR 0.95, 5% CI 0.87 to 1.05 vs HR 0.96, 95% CI 0.86 to 1.08) (figure 3, supplementary table).
In secondary models, individually adding adjustment for HOMA-IR, fasting plasma glucose, 2-h postchallenge glucose, eGFR, ACR, albumin, or liver enzymes (ALT, AST, and γ-glutamyl transpeptidase [GGT]) to the multivariable base model (model 3) had minimal influence on results in either sex, with one exception.
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