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However, given the data included in this review, we have drawn some insights and conclusions that add to the conclusions drawn based on reviews of the BPA literature prior to 2007, categorized by the strength of evidence presented.
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The manuscript would also benefit from adding to the conclusions some general discussion about why this problem is important and what tasks can now be tackled with the benchmarking done in this paper.
Origin of proteins is, generally, outside the scope of this paper (it is relevant only inasmuch as introns are implicated) but a clarifying comment on this issue was added to the Conclusions.
Author's response : The following passage was added to the conclusions section based on the suggestions made by Mushegian and Krupovic: "The presence of non-retroviral RNA virus genes in cellular genomes [[ 61- 66] ] suggests that some cellular mechanism exists that allows RNA-DNA recombination in lieu of a virus-derived RT.
The Reinhart-Rogoff data on aftermath of crises actually came well into this debate, but added to the conclusion that the recovery from 2008-2009 was likely to be nothing like the recovery from 81-82 or 74-75 74-75
Our study adds to the conclusion that pollution may increase systemic inflammation even in young healthy subjects.
5 30–33 This study adds to the conclusion that geographical variation in known cardiovascular risk factors only partially explains this effect.
The considerable and consistent detail in the data also adds to the conclusion that there is high content validity in the material [ 32].
Also, the similar decrease in the PASI as well as SAPASI scores and the visual severity assessment score adds to the conclusion of similar effectiveness.
Second, and supported by the facilitator's report, two of the project investigators reviewed all responses generated by participants to confirm or add to the facilitators conclusions.
A section titled "reviewer's conclusion" was added to the end of the instrument to allow the reviewer to reflect on their findings after the evaluation of an article using the new instrument is complete.
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