The relationship between regulatory input signals and gene expression profile is a complex mapping [8], [9], [10], [11], [12] and combinatorial regulatory inputs add further complexity to the entire framework [8], [10], [13].
Meanwhile the many tippings of the torso (so often sideways) add further complexity, as do changing meters and phrasings.
Weather conditions, such as the intensity and direction of the wind while spraying, add further complexity to the problem of maintaining control.
Changes in plasma temperature, scale height and transport processes add further complexity which makes it difficult to investigate and model the ionospheric behaviour during this transitional period from night to day.
To add further complexity, it is not clear whether carrying capacity was intended as a dynamic concept subject to temporal variability as it was often applied in the reviewed studies.
To add further complexity, recent data suggests that Vfr may control expression of some genes in a cAMP-independent manner [15].
To add further complexity, gene expression programs ongoing in SO myofibers may also recruit nuclear proteins containing PDZ, LIM, or ankyrin domains, and therefore involved in protein-protein interactions.
Our results showing that H-Ras proteins can be direct targets for modification by this compound add further complexity to this picture and call attention to the need of interpreting these results cautiously.
General practice is undergoing structural and demographic changes which add further complexity to estimating future supply.
