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The good news is that aggressive reforestation could add a safety margin and reduce the imminence of the tipping point.
A concentration about 10 times higher than that measured in maize pollen was used to achieve a worst-case exposure scenario and to add a safety margin and thus increase the certainty of the hazard assessment [4], [5].
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A transversely mounted in-line engine frees up more "crush space" than a V, adding a safety margin in collisions, according to Volvo, which uses transverse in-line fives and sixes in its S80 sedan and XC90 sport utility.
After adding a safety margin of 50 nucleotides up- and downstream of the insertion coordinates, primers were selected using BatchPrimer3 v2.0 [ 59].
The carbon ion boost will consist of the GTV including the area of contrast enhancement on T1-weighted MR-imaging; the CTVCarbon for the boost will be defined adding a safety margin of 5 mm.
The Gross Tumor Volume (GTV) will be defined for the carbon ion treatment as the area of contrast enhancement on T1-weighted MR-imaging; the Clinical Target Volume (CTV) will be defined as the GTV adding a safety margin of 5-10 mm depending on the clinical situation and the location of the lesion to account for potential microscopic spread.
We compare this approach with the traditional use of unbiased surrogates (that is, without adding any safety margin).
For a given value of E MSC, the volume of the water reservoirs is calculated by multiplying the flow rate in generation mode by E MSC /8.5 h, adding a 20% safety margin.
This was recognized in legislation such as the Food Quality Protection Act of 1996, which defined new limits for pesticide exposures and added a tenfold safety margin to previously established limits to provide better protection for children.
The PTV is a safety margin that is added to the CTV to allow for set-up errors and movement.
An alternative approach to creation of the PTV is postulated by McGibney et al. [ 10], focusing on the GTV which has the high tumour cell density to which a safety margin must be added for geometric uncertainties.
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