Brentuximab vedotin (an anti-CD30 ADC) [ 34, 87] and BT062 (an anti-CD138 ADC) both incorporate chimeric mAbs [ 88].
Stage III: 10G (ADC), 10H (CC-ADC), 10M (serous surface papillary carcinoma), 10N (papillary serous cystadenoma).
Similarly, lymphomas show significantly lower ADC values as compared to Ig-G4 related disease (mean ADC 1.67 × 10 −3 mm2/s) [69] as well as metastases (ADC range 0.9-1.6 0.9-1.6 mm2/s) [9, 10, 12].
In samples with persistent and significant ADC increases at 20 min, the percentage change in mean ADC 1 5 min after sonication was significantly greater than in samples without persistent ADC changes (11.3 ± 4.9% versus 5.8 ± 3.4%, p = 0.009).
If a UE's received signal is much stronger than the one of another UE, then the weak signal can be drowned out by the strong signal due to the limited quantization resolution of the ADC [1].
ROC analysis showed that a 9% increase in ADC 1 5 min after sonication separated samples with significant ADC increases that persisted 20 min after sonication from those that did not with 69% sensitivity and 89% specificity (area under the curve (AUC), 0.80).
Figure 5 Noise PSD at the output of the ADC (100 MS/s).
Lymphomatous tissue shows high signal on DWI and low ADC [14].
The ADC (ADC12D1800RFRB) has 1.8 Giga samples per second sampling rate and 12 bits resolution.
The scanning voltage is read by an analog-to-digital converter (Hytec ADC 521).
