Exact(16)
Long-term intake of ethanol produces adaptive alterations in multiple transmitter systems in the hippocampal formation that likely contribute to ethanol withdrawal-induced seizure and excitotoxicity.
Because most of the pharmacological actions of benzodiazepines are mediated through GABAA receptor binding, adaptive alterations in the number, structure, and/or functions of these receptors may play an important role in the development of tolerance.
Thus, the observed reduction in mortality with shorter photoperiods may be the consequence of adaptive alterations in immunity.
The molecular changes may rather be adaptive alterations than be the driving forces of malignant progression [29].
The main pathophysiological pathway proposed here is that oxidative stress induces (non) enzymatic initially adaptive alterations in, for example, membrane lipids (LPOs).
In addition to Schwann cells and axons, adaptive alterations in permeability of the BNI can be initiated and effected through immune responses.
Similar(44)
We may conclude from this result that in the case of vascular first fitted amputees balancing on one leg is deemed to feel more safe than standing on two legs which most probably needs an adaptive alteration in balance strategy.
Presumably there must be an adaptive alteration in the change of position, from the origin of the hip joint in the first few weeks of embryonic life to the 90 degrees of rotation and adduction of the hip in the second four weeks of life.
We therefore conclude that age-related alterations are composed of plastic-adaptive alterations in response to modified use and degenerational changes developing with age.
At the molecular level, this occurs presumably through a mutational burden of non-adaptive alterations or epigenetic modifications ('genetic load').
No studies have examined whether this is related to impaired cardiovascular compliance as a consequence of loss of adaptive structural alterations, resulting from chronic uremia or hypertension.
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