There is a class of theories of aging (variously termed adaptive aging, aging by design, aging selected for its own sake, or programmed death theories) that hold that an organism design that limits life span conveys benefits and was selected specifically because it limits life span.
In acknowledging that at least in theory, aging might occasionally be adaptive, however, the high barriers to validating actual instances of adaptive ageing are made clear" [ 1].
Technologies for adaptive aging include: wireless broadband; biosensors and bodily diagnostics; activity sensors and behavioral diagnostics; information fusion; personal health informatics; ambient displays and actuator networks; agents, assistants, coaches, and companions; adaptive, distributed interfaces; and remote community and collaboration (Dishman et al 2004) (See Table 2).
In contrast to the changes in adaptive immunity, age-related alterations in innate immunity are less well defined.
Sommer et al. suggested that only 28% of the children born by adolescent mothers scored within normal ranges on personal adjustment and intellectual linguistic development, social emotional functioning, and adaptive behavior at age 3 years [26].
The analysis also showed a weak negative association between their adaptive capacity and age (r = − 0.026; p ≥ 0.05).
Poverty, low education level, AC prevalence, and social isolation were indicators of adaptive capacity; ethnicity, age, and diabetes prevalence were indicators of a population's sensitivity to heat; and density of green space indicated both physical exposure and adaptive capacity.
This suggests that the deposit represents an early adaptive response to aging, which might consequently provide aged cells some advantage over their younger counterparts.
However, the observed dynamic changes may also result from a healthy adaptive response to aging (hormesis), which maintains the important functions of mitochondria at the synapse and potentially contributes to aging via mitochondrial hyperfunction.
Error-prone transcription has been proposed to contribute to cancer, aging, adaptive mutagenesis, and mutagenic evolution of retroviruses and retrotransposons.
