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We then adapted the procedure of Mume et al. [ 33] that used DTT to reduce the protein and then removed the excess DTT using a NAP-5 column before conjugation.
In order to access the 3-substituted heterocycles 1– 6, we adapted the procedure of MacCoss et al. to give 3-aryl substituted 8-chloroimidazo[1,2 a]pyrazines from 2-aryl-2-hydroxy amines 14a– e (Scheme 1).
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We adapted the procedures of Chalin and Mollison 8 and Bernstein 9 to compare the fraction of plasma trapped in the erythrocyte column of samples centrifuged in the ZIPocrit and hand-powered centrifuges.
We adapt the procedure of [17], adjusting it for our big data.
In particular, we propose a method based on the gradient direction variance and a wavelet-based method which adapts the procedure of [14] to videokeratoscopic images.
By incorporating this information, our method implements a more biologically accurate model of the k-mer abundance distribution, adapting the procedure of [ 22] to high-coverage (>30×), short-read sequences.
The total phenolic and flavonoid content were analysed by adapting the procedure of Maria John et al. [ 11] and Yoo et al. [ 12] using 96 well microplate reader (SpectraMax Plus384 Devises, CA, USA).
Other quantitative phenotypes or experimental techniques for defining or measuring genetic interactions could, in principle, also be used, although certain modifications will be needed to adapt the procedure to the specific characteristics of each genetic interaction screen.
To obtain mica flakes on semitransparent gold layers, we adapted the procedure previously developed for the fabrication of flat gold substrates[8].
The goal of learning to hash is to learn data-dependent and task-specific hash functions that yield compact binary codes to achieve good search accuracy, where sophisticated machine learning tools and algorithms have been adapted to the procedure of hash function design [54, 55].
The dispersion protocol of SWCNT-PEG was adapted from the procedure of Kalinina et al. [ 19] and employed several steps of mechanical disintegration and centrifugation.
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