Afterwards, membranes were probed overnight at 4°C with an adapted concentration of each antibody followed by the appropriate HRP-conjugated antibody for 1 h at room temperature (1 : 2000).
To do this we developed and used a methodology based on assuming that, for policy purposes, the risks to health from IAP can be approximated by adapting concentration-response functions from outdoor air pollution, in the metric of PM2.5.
Calcium administration was adapted to concentrations of ionized calcium in the patient by a specially designed algorithm, as described before [ 12].
Calcium administration was adapted to concentrations of ionized calcium in the patient by an especially designed algorithm, as described before [ 22].
Microcosms were started with sludge from two treatment plants as inoculum; (i) a sludge that was adapted to concentrations of pharmaceuticals and (ii) unadapted sludge from an MBR reactor sampled shortly after start-up and only exposed to low concentrations of pharmaceuticals.
Calcium administration was adapted to concentrations of systemic ionised calcium by a specially designed algorithm, targeting systemic ionised calcium levels of 1.0 to 1.35 mmol/L [ 19]; for calcium pump settings see Additional file 1. Calcium levels in the extracorporeal circuit were not measured routinely, in order to keep the treatment protocol simple.
Moreover, on the basis of the heuristic method adapted from concentration interval analysis method for the continuous process network design, the network design for the discontinuous or batch process can be obtained through the designs for every time interval.
Thereby, PTX was administered 24 h post RIT in order to adapt peak concentrations of 177Lu-DOTA-chCE7 177Lu-DOTA-chCE7 177Lu-DOTA-chCE7
A drug intake of approximately 30 mg/kg/day was achieved by adapting the concentrations of the NK1 receptor antagonist in the drinking solutions according to mean drinking volume and body weight per cage.
Mass concentrations adapted from measurements taken in the National Library in Prague [24] and completed with theoretical number concentration of ultrafine particles according to [26].
