Since antifungal drug therapy has a short history, we have to emphasize that adaptation to polyenes by modification of the PDR5 gene, on the assumption that it did occur, likely represents an evolutionary force that selected a pre-existing genetic variation.
During adaptation to restricted fetal development, modifications to nuclear receptors act to optimize growth and differentiation.
It is thought that adaptation to sea anemones required modifications of the general shape as well as a change in swimming ability in host specialised clownfish.
Therefore our results suggest that, even if some modifications occurred directly in the presence of pain[ 11, 14], adaptation to low back pain and modifications of motor control strategies are not implemented spontaneously.
The CBMN test was performed according to the original method [ 33] with marginal modifications for adaptation to A549 cells.
Such a change in the expression of genes involved in lipid and ergosteols metabolism may lead to membrane modification, possibly facilitating adaptation to alkanes exposure.
The Article provides that all existing laws shall continue in force after the commencement of the Constitution subject to "modifications, adaptations, qualifications and exceptions as may be necessary to bring them into conformity" with the Constitution of Singapore.
Consequently, our predictions of species adaptations to the ongoing environmental modifications remain elusive.
In [ 1] adaptive designs are defined as: "...a clinical trial design that allows adaptations or modifications to aspects of the trial after its initiation without undermining the validity or integrity of the trial.
(5) If an Act of Tynwald or an instrument made under an Act of Tynwald so 30 provides, this Measure extends to the Isle of Man, subject to such exceptions, adaptation or modifications as may be specified in the Act of Tynwald or instrument.
