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Skeletal muscle adaptation to exercise training: AMP-activated protein kinase mediates muscle fiber type shift.
Efficient adaptation to exercise training requires optimal exposure to pulses of RONS.
Innovative research strategies are needed to define the molecular mechanisms involved in adaptation to exercise and to translate them into useful clinical and public health applications.
For several of the mechanically loaded connective tissues, only limited information regarding molecular and cellular signaling pathways and their adaptation to exercise is available.
In their legs, genes were being expressed that activated growth factors that, in turn, increased levels of "important enzymes associated with cell defense" and "adaptation to exercise," the researchers wrote.
This capacity to improve is linked to physical adaptation to exercise, which is partially genetically mediated.
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As age and chronic disease can impair muscular adaptations to exercise, knowledge of the pathways that regulate adaptive reprogramming in muscle will be invaluable for designing strategies to improve muscle function in specific clinical populations.
Individuals differ in both physiological and psychological adaptations to exercise.
Signaling mechanisms in skeletal muscle: acute responses and chronic adaptations to exercise.
Furthermore, indications of reduced cardiometabolic adaptations to exercise in postmenopausal women add to the adverse health profile.
Thus, there is an important need to identify adjuvant therapies capable of augmenting mitochondrial adaptations to exercise (e.g. improved mitochondrial respiration, muscle mitochondria biogenesis) among older adults.
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