Proponents of adaptation on the one side and mitigation on the other have each been overemphasizing their own problem and suggested solutions, while disregarding the other side [17].
The up-regulation of glycolysis and the induction of microenvironmental acidosis after bevacizumab treatment may lead to a cellular adaptation, on the one hand maintaining continued tumor growth and on the other hand promote invasion.
While such determinism speeds adaptation on the smooth adaptive landscape represented by the simple environment, it can limit the ability of large populations from effectively exploring the underlying topography of rugged adaptive landscapes characterized by complex environments.
In addition, 48% of all SNPs found to change frequency significantly on one diet also showed significant adaptation on the second dietary replicate, an overwhelming proportion given the independent population dynamics in each replicate.
In addition, a range of resources – from grants and loans to fiscal measures and market-based instruments – will be needed for successful mitigation and adaptation on the ground.
When I next read the book, and recently, while listening to Rachel Joyce's luminous adaptation on the radio, I was struck by the extraordinary directness with which Rochester and Jane communicate.
(An appealing musical adaptation, "On the Twentieth Century," was staged in 1978.) "A 'Grand Hotel' on wheels" was the way one critic described the play when it opened in 1932.
(The most notable adaptation on the menu at Chinese Mirch is its omission of pork and beef, which are forbidden, respectively, to Muslims and Hindus, the two dominant religious groups in India).
Figure 2 Local adaptation on the S-potential response curve.
These solutions prove simplicity in adaptation on the representative operating points.
