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Cytokeratin 20 and uroplakin II expression could be induced by adaptation of the cells to hyperosmolal culture conditions.
Although the knockdown (KD) efficiency was less than 100%, we used this method rather than performing gene knockouts because, in addition to the direct effects of gene knockouts, secondary effects may also be observed that are caused by adaptation of the cells during long-term culture.
Adaptation of the cells to the osmostress situation temporally correlates with the dephosphorylation of AdcA.
The duration of the transient transducer demethylation approximately correlates with the kinetics of behavioral adaptation of the cells [ 35].
In yeast the HOG signalling pathway is responsible for the adaptation of the cells to high osmolarity.
The results obtained concerning the production of free radicals may suggest an adaptation of the cells to irradiation.
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Since the load situation is very dependent on the location of the small cell and is varying heavily over time, a dynamic adaptation of the cell range expansion is an attractive solution to optimise the overall system performance.
The adaptation of the cell size needs to be signalled to the UEs, and therefore, it is typically done with a periodicity of 1 to 10 s or even longer [16].
Ectoine and 5-hydroxyectoine belong to the family of compatible solutes which are known to mainly contribute to the adaptation of the cell to osmotic stress by mediation of a constant turgor.
These observations are compatible with metabolic adaptation of the cell to carbon starvation.
In addition, we propose that glycosylation of its carotenoids plays a crucial role in the adaptation of the cell membrane to this bacterium's thermophilic lifestyle.
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