The phrase "adaptation of signalling" is correct and usable in written English.
It can be used in contexts discussing changes or modifications to communication methods or systems, particularly in fields like biology, technology, or communication studies.
Example: "The adaptation of signalling in the organism allowed it to better respond to environmental changes."
Alternatives: "modification of signaling" or "adjustment of signaling".
The observed order of events with immediate adaptation of signaling pathways over transcriptional reprogramming and eventually presumed outgrowth of genetically resistant clones suggests that there may be a finite number of escape pathways, and inhibitors to target them may already be available.
By the same token, Grover et al. (2003) showed that Alu elements are more clustered in genes involved in metabolism, transport, and signalling processes (facilitating the adaptation of signal transduction pathways to environmental changes) than in genes encoding information pathway components and structural proteins [ 11].
It would not be surprising then to find evidence for the chemical adaptation of signal sequences to specific compartments.
Whether these regulatory characteristics apply to the putative related rice molecules OsRR8, 12, 13 and 13H remains to be determined [ 6, 27], but if so, it points to a conserved adaptation of this type of signalling pathways to reproductive specific functions.
This phenomenon of 'withdrawal relief' provides evidence of an ethanol-induced adaptation which resets the balance of signalling in neural circuits.
Signaling cross-talks are important connections between different pathways and can generate novel input output combinations as well as maintain the dynamic adaptation of the signaling system [ 39, 40].
Vascular graft adaptation also requires activation of signaling pathways activated by high shear stress to promote healing of the graft by preventing intimal proliferation (Kohler et al., 1991).
Hence, these results suggest that Bax and Bcl2 heterogeneities impact mitochondrial (and hence cellular) activity at different stages of signaling adaptation, and the emergence of sub-populations help explain the observed extensive cell-to-cell variability even under conditions of constitutively-active LIR and high AV content.
That design adaptation is significant because the kind of signaling the brain uses is thought to be very different from that used in digital computers.
This observation can be explained by adaptation of the transcriptional network and of signaling pathways to cell culture conditions.
