The investigations and road-mapping processes lead to structural changes towards new generations of adaptable factories - engineered with knowledge-based engineering systems and operating in an ubiquitous information and communication (Grid Manufacturing) environment.
We engineered adaptable 3D tumor organoids presenting adhesive peptides with distinct integrin specificities to B and T cell lymphoma cells that resulted in enhanced proliferation, clustering, and drug resistance to the chemotherapeutics and a new class of histone deacetylase inhibitor (HDACi), Panobinostat.
Thus, if the final system should be usable, testable, secure, high performance, mobile and adaptable, then these qualities or non-functional requirements (NFRs) should be engineered into the architecture itself.
A potentially more interesting approach allowing for autonomous and adaptable training could be to engineer an additional synthetic gene circuit controlling cell growth based on the output signal, using for example one of well-characterized positive/negative selection systems.
To Mr. Evans, fast and cheap — and highly adaptable — is good by definition, allowing engineers to identify needed updates, repairs and new features.
Beloved of engineers, the traditional pylon is adaptable and, like Meccano, can be adjusted as the landscape requires, with options for lower height near airfields or huge towers to cross rivers.
The hillside home Ms. Leibrock shares with her husband, Frank, a retired engineer, is not wheelchair accessible, but it is wheelchair adaptable, Ms. Leibrock says.
The two engineers started Picochip with the idea of making wireless chips that would be adaptable to a range of tasks.
They are very adaptable".
