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With the increasing number of novel agents and delivery techniques being explored in clinical trials there is a strong need for robust and adaptable criteria to monitor response assessment and thus define endpoints.
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Results revealed that our two-step approach with adaptable FD detection criteria gives rise to more reliable and stable measures in low- and high-quality data.
The goal of the present paper is to develop a criterion and use an adaptable die design methodology that will allow the prediction of extrusion die shapes that produce minimum distortion in axisymmetric product.
A variety of criteria can be used in the adaptable die design method.
One befriending programme rated potential volunteers from 0 to 10 on the criteria: 'reliable, responsible, conscientious, has initiative, adaptable, prepared to receive and accept feedback, good listening skills, non-judgemental, ability to learn new skills, and awareness of boundaries' [ 22].
The new in vitro multiple stress dormancy model efficiently generates Mtb cells meeting all criteria of dormancy, and this method is adaptable to high-throughput screening for drugs that can kill dormant Mtb.
The results provide further support for the findings that the average effective strain and the volumetric effective strain rate deviation are robust criteria, which can be used to determine optimal adaptable die shapes with an upper bound model.
Although the criteria are results-oriented, they are non-prescriptive and adaptable, so that organizational structure and quality approaches may differ widely from one organization to another.
The developed course offers a cross-professional design in a readily adaptable structure, is focussed on actual scenarios, and has been aligned with quality criteria for improved teaching approaches [14, 16, 19].
Based on the use of the volumetric effective strain rate deviation criterion, extrusion dies, which minimize distortion, are established using the adaptable die design methodology.
The adaptable design method uses upper bound models to determine die shapes that meet specified criteria, such as minimizing distortion in the product.
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CEO of Professional Science Editing for Scientists @ prosciediting.com