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A comprehensive toxicology assessment was not performed for this molecule, however, we did not see any evidence of adverse effects when AC163794 was tested acutely up to 6 mg/kg (˜1400 nmol/kg) in mice.
Similar(59)
Second, the large phase IIb run length peak is absent in the t = 3 null, consistent with the hypothesis that BicD can acutely up-regulate both directions of transport.
Both TL1A and DR3 expression levels are low under physiological conditions, but can be acutely up-regulated in inflammatory reaction.
Following 24 hr 5-FU exposure, nearly all of the acutely up-regulated genes had returned to baseline levels.
The pro-apoptotic protein Gadd153 is acutely up-regulated by several stresses encountered during the large scale culture of mammalian cells.
G2A and SDCCAG33 were acutely up-regulated by 5-FU treatment whereas TSC2 was a delayed response gene affected by 5-FU.
Specifically, IGFBP-3 mRNA is acutely up-regulated in the mouse brain in response to transient ischaemia (O'Donnell et al., 2002), a response that was associated with the post-ischaemic inflammatory response.
While IRIS can occur acutely for up to 18 months after initiation of ART, most cases occur within the first two weeks to two months after initiation.
It's not a term I've heard before, but I think it acutely sums up the cultural problem that we're grappling with," he said.
Born biologically female, Zoltar grew up acutely aware that he was set apart from other children.
I grew up acutely aware of how tenderly he and my grandmother felt toward each other, especially in comparison to my maternal grandparents, who seemed to be constantly bickering and never displaying affection.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com