Sentence examples for acutely disrupt from inspiring English sources

Later, using a chc1 temperature-sensitive allele, it became possible to acutely disrupt clathrin function, which led to reduced endocytosis within 2 min of temperature shift (Tan et al. 1993).

Enrichment of CCVs and a corresponding reduction in the number of bona fide SVs was also observed in stimulated lamprey reticulospinal synapses following microinjection of mammalian intersectin 1-SH3B to acutely disrupt intersectin/endophilin complex formation in situ (Supplementary Fig S2A, C H).

A significant delay in barrier recovery is seen when acutely disrupted skin sites are immersed in neutral pH buffers.

The advantage of this approach over pharmacology or genetic manipulation is that it acutely disrupts the inhibition impinging on a single RGC while leaving excitatory inputs and the rest of the retinal circuitry intact; a similar approach was used to demonstrate direction selectivity occurs postsynaptically in direction-selective RGCs (Taylor et al., 2000).

Using pharmacological inhibitors on neurons migrating in vitro affords the opportunity to disrupt endocytosis acutely and observe consequent migratory behavior.

Holmes says she is acutely aware that technology could disrupt Theranos.

Concentrations as low as 250 ppm toluene were able to disrupt auditory function acutely in the guinea pig, and 500 and 1000 ppm toluene produced greater acute dysfunction.

Alcohol may disrupt orientation selectivity by acutely suppressing NMDA receptor function [10], [23], [68] while enhancing GABA receptor function [69] thereby affecting CREB phosphorylation [70] [72].

Unlike acutely transforming retroviruses, these retroviruses do not disrupt normal cellular functioning through insertion of a viral oncogene.

Chang et al. found that light levels of the range of approximately 30 to 50 lux in the angle of gaze delayed the circadian clock, acutely suppressed melatonin and disrupted sleep [ 19].

Given that the mushroom body is likely involved in complex spatial orientation (Zhang et al. 2007) and memory-related tasks (Krashes et al. 2009), silencing of this brain structure could disrupt both positional repulsion and egg-laying attraction at more global levels of informational processing, rather than acutely interfering with integration of signals from the two sensory pathways.