Sentence examples for acutely challenging from inspiring English sources

Like any leisure industry, racing faces an acutely challenging year.

The acutely challenging issue is to design the SBE not only to satisfy multidisciplinary requirements but also to orchestrate the technical functions of components.

However, a particularly cold winter made winter mining more acutely challenging, the company reported, coupled with the mining of lower-grade diamonds, which resulted in a 31.0% decrease in recovered carats, compared to the corresponding quarter last year.

That same year, the severe acute respiratory syndrome (SARS) epidemic acutely challenged the response capacity of scientists and public health officials across the globe [ 3, 4].

ADH transgenic and wild-type FVB mice were acutely challenged with ethanol (3 g/kg/d, i.p).

When acutely challenged by environmental or physiological stress, the integrity of distal axons must be acutely independent of neuronal gene transcription [ 56].

While the long-term metabolic stress of diabetes and obesity leads to haemodynamic dysregulation [ 4, 26], cardiovascular function is also acutely challenged in the perioperative setting [ 4, 27].

Indeed, microsomal vesicles rapidly released their accumulated Ca2+ when acutely challenged with 6-OH-BDE-47 (10 μM), and this effect was completely blocked by RR.

Myeloid/haematopoietic Fas deficiency prevented the development of glucose intolerance in high fat-fed mice, in ob/ ob mice, and in mice acutely challenged by LPS.

After incubation in the absence of metformin, the islets pre-exposed to 22.2 mmol/l glucose showed no significant increase in insulin release when challenged acutely with 16.7 mmol/l glucose (confirming that hyperglycemia desensitizes pancreatic β-cells).

Together the group explores solutions and realise – acutely – the challenges these women face.